Table 1.
Effect of oral administration of gallic acid (GA) on the induction of individual chromosomal aberrations, polyploidy, SDC, pulverization, and number of aberrations per cell in mouse bone marrow cells by whole body gamma irradiation (2 Gy).
| Treatments | Breaks (%) | Ring (%) | Dicentric (%) | Aberrations/cell | Pulverisation | Polyploidy | SDC |
|---|---|---|---|---|---|---|---|
| Normal | 1.4 ± 0.89 | 0 ± 0 | 1 ± 0.58 | 0.024 ± 0.015 | 0 ± 0 | 0 ± 0 | 0 ± 0 |
| GA | 1.2 ± 1.09ns | 0 ± 0ns | 0.8 ± 0.84ns | 0.02 ± 0.019ns | 0 ± 0ns | 0 ± 0ns | 0 ± 0ns |
| 2 Gy | 29.8 ± 2.89 | 8.7 ± 2.59 | 10.5 ± 0.47 | 0.49 ± 0.04 | 2.4 ± 0.81 | 5.6 ± 0.5 | 1.6 ± 0.46 |
| GA + 2 Gy | 9 ± 0.71$ | 3 ± 0.70$ | 2.5 ± 0.35$ | 0.145 ± 0.02$ | 0 ± 0$ | 1 ± 0$ | 0 ± 0$ |
ns: not significant, $: P < 0.001, when compared with respective controls.