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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Dev Dyn. 2013 May 30;242(7):897–908. doi: 10.1002/dvdy.23978

Figure 1. Comparison of Zic genes across species.

Figure 1

(A) Phylogenetic tree showing the relationships among the Zic genes from human, mouse, chick, zebrafish, and frog, as well as the ancestral gene odd-paired (opa) from Drosophila. The complete amino acid sequences were used for the construction of the tree. (B) Percent identity and similarity of the amino acid sequences among the mouse, chick, and human ZIC proteins. The chick ZIC2, ZIC3, and ZIC4 protein sequences have not been finalized, so comparisons to these protein sequences result in much lower percent identity and similarity. Abbreviations: Dm, Drosophila melanogaster; Dr, Danio rerio; Gg, Gallus gallus; Hs, Homo sapiens; Mm, Mus musculus; Xl, Xenopus laevis