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. 2013 Aug 6;32(17):2377–2391. doi: 10.1038/emboj.2013.178

Figure 9.

Figure 9

Chemical inhibition of NFκB and PI3K pathways prolonged the survival of mice bearing miR-17∼92-driven lymphomas. (A) TG lymphoma transplantation and treatment scheme. (B) The size of tumour at injection site on day 15, 17, and 19 post transplantation. Tumour size below the measurable range was given an arbitrary value of 1. Each dot indicates one experimental mouse. **P<0.01; ***P<0.001; ****P<0.0001. (C) Kaplan–Meier survival curve analysis of recipient mice treated with vehicle, AZD8055 (P=0.0002), or BMS-345541 (P=0.0136).