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. 2013 Aug 28;2013:676049. doi: 10.1155/2013/676049

Table 3.

Association between single-nucleotide polymorphisms and changes in visual acuity score and central retinal thickness.

SNP VA score change CRT change (μm)
Letters ≥15 letters gain N Median P*
N Mean ± SD P n (%) P
CFH rs800292
 TT 11 17.6 ± 17.6 0.065 7 (63.6) 0.041 11 −120.0 0.620
 TC 56 10.0 ± 14.0 19 (33.9) 53 −47.0
 CC 73 7.3 ± 13.1 19 (26.0) 65 −71.0
ARMS2 rs10490924
 GG 16 12.4 ± 10.9 0.005 6 (37.5) 0.015 16 −134.0 0.445
 GT 44 14.0 ± 13.5 21 (47.7) 38 −69.0
 TT 83 6.0 ± 13.9 19 (22.9) 77 −81.0
HTRA1 rs11200638
 GG 16 12.4 ± 10.9 0.002 6 (37.5) 0.027 16 −134.0 0.473
 GA 43 14.5 ± 12.7 20 (46.5) 37 −71.0
 AA 85 5.9 ± 14.1 20 (23.5) 79 −81.0

CRT: central retinal thickness; SD: standard deviation; SNP: single-nucleotide polymorphism; VA: visual acuity.

*Nonparametric testing.