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Pandemics of Shiga dysentery. The first member of the genus Shigella to be isolated, Shigella dysenteriae 1, was isolated by Kiyoshi Shiga during epidemics that occurred in Japan in the 1890s. Beginning in Central America in the late 1960s, pandemics of S. dysenteriae 1 caused severe disease with many complications and high case-fatality rates in all age groups. Subsequent pandemics occurred in Asia and Africa over the following 3 decades.
