Table 2.
Predictors of Medication Discontinuation After Myocardial Infarction
| Statins (n=219) | Beta-blockers (n=248) | ACE Inhibitors/ARBs (n=180) | ||||
|---|---|---|---|---|---|---|
| Variable | Hazard Ratio | 95% CI | Hazard Ratio | 95% CI | Hazard Ratio | 95% CI |
| Age (per year increase) | 1.01 | 0.99-1.02 | 1.00 | 0.99-1.02 | 1.00 | 0.99-1.02 |
| Male sex | 0.82 | 0.58-1.17 | 1.01 | 0.72-1.40 | 0.84 | 0.57-1.24 |
| Current Smoker | 1.20 | 0.81-1.77 | 1.39 | 0.98-1.97 | 1.32 | 0.86-2.02 |
| Received reperfusion or revascularization therapy | 0.96 | 0.65-1.40 | 0.80 | 0.57-1.14 | 0.96 | 0.62-1.49 |
| Enrolled in cardiac rehabilitation program | 0.66 | 0.45-0.92 | 0.70 | 0.49-0.98 | 0.70 | 0.45-1.10 |
| aNumber of comorbidities | 1.04 | 0.93-1.16 | 1.00 | 0.90-1.11 | 1.00 | 0.88-1.13 |
Determined from comorbidities used to calculate the Charlson comorbidity index
ACE-I/ARB= angiotensin converting enzyme inhibitor/ angiotensin II receptor blocker