Fig. 5.
The SAM/SAH ratio decreased in rat liver perfused with ethanol (EtOH, 20 mM) or propanol (Prop, 20 mM). The SAM/SAH ratio was calculated from the hepatic concentrations of SAM and SAH. The ratio was restored by infusion of 4-methylpyrazole (4-MP, 4 mM) or pyruvate (10 mM). Groups that do not share a common letter are significantly different (p<0.05).