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. 2013 Sep 2;8:3321–3331. doi: 10.2147/IJN.S47742

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© 2013 Wu et al. This work is published by Dove Medical Press Ltd, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Ltd, provided the work is properly attributed.

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Cytotoxic response of different cell lines shows different sensitivity toward Fe@Au or Fe-only nanoparticle treatments.

Notes: CRC and OECM1 were treated with Fe-only nanoparticles (Fe NPs) and Fe@Au nanoparticles (Fe@Au NPs) for 48 hours, analyzed by WST-1. OECM1 and Caco-2 are more sensitive to Fe nanoparticles; whereas, the other CRC, (HT-29 and SW480) are more resistant to Fe nanoparticles than to Fe@Au nanoparticles. (*P & 0.05; t-test).

Abbreviations: Fe, iron; Au, gold; NPs, nanoparticles; WST-1, water-soluble tetrazolium salt; CRC, colorectal cancer.