FIGURE 6.

HDL, but not LDL, stimulates basal tocopherol secretion by Caco-2 monolayers. Monolayers were treated with BMS201038 and mixed micelles, with or without T0901317 as in Fig. 1 and 2. Either HDL (0, 6 or 12 μg/mL)(A) or LDL (0, 6 or 12 μg/mL) (B) were added to the basolateral compartment at 0 h, and basal tocopherol was determined after 24 h. Results are expressed as means ± SDs (HDL, n = 9; LDL, n = 3). *P < 0.005 vs. 0 μg/mL; given a vitamer and treatment, labeled means without a common letter differ, P < 0.01. HDL, high density lipoprotein; LDL, low density lipoprotein; TOH, tocopherol.