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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Mol Nutr Food Res. 2013 May 3;57(10):1718–1728. doi: 10.1002/mnfr.201200794

Figure 5.

Figure 5

XN treatment inhibits hepatic lipogenesis and induces fatty acid oxidation in ApoE−/− mice. Female ApoE−/− mice were fed WTD ± XN for 8 weeks. Livers were excised and protein as well as total RNA were isolated. (A) Quantitative realtime PCR analyses of SREBP-1c, SCD1, and (C) CPT-1a normalized to cyclophilin A. Data are expressed as mean values (n = 4) ± SD. *p < 0.05, ***p ≤ 0.001. (B) Western blotting analyses of proteins involved in fatty acid and cholesterol biosynthesis. Band intensities were quantitated using Image J software. Data represent the ratios of pACC/ACC, pAMPK/loading control, and mSREBP2/SREBP2 from three samples per group ± SD. *p < 0.05, ***p ≤ 0.001.

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