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XN treatment enhances fecal cholesterol excretion in ApoE−/− mice fed WTD. Female ApoE−/− mice were fed WTD ± XN for 8 weeks. (A) Representative Western blot analysis of ABCG1 from liver lysates of two untreated (−) and two XN-treated (+) mice. The bar graph represents quantifications from samples of n = 4 ± SD. *p < 0.05. (B) Fecal cholesterol levels calculated as mean concentrations (n = 5) ± SD of feces collected for three consecutive days. **p ≤ 0.01.
