Table 1.

Reduced plasma cholesterol concentrations in XN-fed ApoE^−/− mice

	4 weeks		8 weeks
	WTD (n = 10)	WTD + XN (n = 13)	WTD (n = 8)	WTD + XN (n = 9)
TC (mmol/L)	23.8 ± 1	16.3 ± 1***	26.5 ± 0.8	20.3 ± 1.1***
FC (mmol/L)	7.4 ± 0.4	5.4 ± 0.4**	8.3 ± 0.3	6.5 ± 0.4**
CE (mmol/L)	16.2 ± 0.8	10.9 ± 0.6***	18.2 ± 0.6	13.8 ± 0.7***
TG (mmol/L)	0.8 ± 0.1	0.8 ± 0.1	1.2 ± 0.1	1.5 ± 0.2
XN plasma concentrations
XN (nmol/L)	Fasted plasma n.d.		Fed plasma 61

ApoE^−/− mice were fed WTD ± XN for 8 weeks. Plasma was isolated from overnight fasted mice after 4 and 8 weeks, respectively, and TG, TC, and FC concentrations were measured enzymatically. CE concentrations were calculated as CE = TC − FC.

XN plasma concentrations were measured in pooled samples from WTD + XN-fed ApoE^−/− mice (n = 4) after 4 weeks of feeding.

Data are expressed as mean values ±SD.

^**p ≤ 0.01

^***p ≤ 0.001.

n.d., not detected.