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. 2013 Sep 12;9(9):e1003801. doi: 10.1371/journal.pgen.1003801

Figure 7. The fat-7 desaturase is regulated by paqr-2 and its suppressors.

Figure 7

(A) The paqr-2 mutant has decreased expression of fat-7, while strains carrying the paqr-2 suppressors nhr-49(et8) or cept-1(et10) show a marked increase in fat-7 expression when compared to control worms (wt). (B) The nhr-49(et8) and cept-1(et10) alleles are dependent on both nhr-49 and sbp-1 for the upregulation of fat-7. (C) Representative images of worms from panel (A). Note the strong GFP signal in the paqr-2;cept-1(et10) double mutant, especially compared to the low levels of the paqr-2 single mutant. Scale bar is 100 µm. All strains in this figure carry the fat-7 promoter GFP reporter in integrated form.