Table 4. PCR assay.
Characteristics | n=41 | Active TB | Active TB | Chi-square | Df | P-value | n=84 | Non-TB Control | Non-TB Control | Chi-square | Df | P-value |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Positive | Negative | Positive | Negative | |||||||||
n=20 (49%) | n=21 (51%) | n=2 (2%) | n=85 (98%) | |||||||||
Age | ||||||||||||
<18 | 1 | 0 | 1 (100) | 9 | 0 | 9 (100) | ||||||
18 to 40 | 32 | 17 (53) | 15 (47) | 53 | 2 (4) | 51 (96) | ||||||
>40 | 8 | 3 (38) | 5 (62) | 8.450 | 1 | 0.0037 | 25 | 0 | 25 (100) | |||
Gender | ||||||||||||
Male | 21 | 9 (43) | 12 (57) | 50 | 0 | 50 (100) | ||||||
Female | 20 | 11 (55) | 9 (45) | 0.050 | 1 | 0.8231 | 37 | 2 (5) | 35 (95) | |||
BCG Vaccinated | ||||||||||||
Yes | 12 | 4 (33) | 8 (67) | 23 | 0 | 23 (100) | ||||||
No | 19 | 12 (63) | 7 (37) | 47 | 1 (2) | 46 (98) | ||||||
Don’t Know | 10 | 4 (40) | 6 (60) | 6.400 | 2 | 0.0408 | 17 | 1 (6) | 16 (94) | 0.500 | 1 | 0.4795 |
BMI | ||||||||||||
Underweight (16-18.5) | 18 | 8 (44) | 10 (56) | 22 | 1 (5) | 21 (95) | ||||||
Normal (18.5 to 25) | 19 | 10 (53) | 9 (47) | 60 | 1 (2) | 59 (98) | ||||||
Overweight (> 25) | 4 | 2 (50) | 2 (50) | 5.200 | 2 | 0.0743 | 5 | 0 | 5 (100) | 0.500 | 1 | 0.4795 |
Depict the results of Mycobacterium specific IS6110 (123bp) PCR product in the blood of TB patients and non-TB control individuals in Melghat region. Note: n = no of cases; ( ) = Percentage; BMI = Body Mass Index; PCR = Polymerase Chain Reaction