Table 2. Multiple logistic regression (MLR) and Cox regression analyses to predict mortality in the 292 patients of global cohort (first and second cohort combined).

	MLR OR (95% CI); p-value	Cox regression OR (95% CI); p-value
Model: Mortality at 30 days in global cohort of 292 patients
mtDNA haplogroup JT	0.38 (0.15–0.95); 0.04	0.48 (0.22–0.97); 0.04
Serum Interleukin-6 levels	1.001 (1.0001-1.0015); 0.01	1.001 (1.0001-1.0015); <0.001
Age	1.16 (0.99–1.03); 0.16	1.16 (0.999–1.03); 0.05
Sex female	1.20 (0.66-2.19); 0.55	1.15 (0.73-1.79); 0.55
SOFA	1.15 (1.06–1.24); 0.001	1.15 (1.08–1.21); <0.001
Model: Mortality at 6 months in global cohort of 292 patients
mtDNA haplogroup JT	0.40 (0.17–0.90); 0.03	0.51 (0.26–0.97); 0.04
Serum Interleukin-6 levels	1.0005 (0.999-1.001); 0.052	1.0005 (1.0001-1.001); 0.001
Age	1.02 (1.004–1.042); 0.02	1.02 (1.006–1.034); 0.005
Sex female	1.18 (0.67-2.09); 0.56	1.14 (0.77-1.70); 0.52
SOFA	1.15 (1.06–1.24); <0.001	1.12 (1.07–1.18); <0.001

OR = Odds Ratio; CI = Confidence Interval; SOFA = Sepsis-related Organ Failure Assessment