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The AgDI pathway and organization of the gene cluster in L. monocytogenes. A, the AgDI pathway. Agmatine is first hydrolyzed to form N-carbamoylputrescine by AgDI. N-Carbamoylputrescine is then converted into putrescine and carbamoylphosphate by putrescine transcarbamoylase. Carbamate kinase (CK) then catalyzes the phosphate moiety in carbamoylphosphate to ADP, forming ATP as well as ammonia and CO2. B, genetic organization of the L. monocytogenes agmatine deiminase gene cluster.
