Table 4. Mean angular width and area of photographic RNFL defects and average RNFL thickness according to the presence or absence of RNFL defects.
|
Not detected |
Detected |
P-valuea | ||||
|---|---|---|---|---|---|---|
| No. of eyes | Mean±SD | No. of eyes | Mean±SD | |||
| Angular width of RNFL defects (degree) | ||||||
| 4 sector thickness | (<5% level) | 22 | 16.4±11.7 | 42 | 40.8±20.1 | <0.001 |
| 12 sector thickness | (<5% level) | 14 | 9.9±4.9 | 50 | 38.7±19.5 | <0.001 |
| 36 sector thickness | (<5% level) | 5 | 7.6±4.3 | 59 | 34.5±20.6 | 0.02 |
| Thickness map | b | 2 | 8.9±7.1 | 62 | 33.2±21.0 | 0.08 |
| Significance map | (<5% level) | 1 | 3.9 | 63 | 32.9±20.9 | 0.10 |
| NFL thickness | (<5% level) | 14 | 12.2±8.3 | 50 | 38.1±20.1 | <0.001 |
| GCL+IPL thickness | (<5% level) | 27 | 20.8±15.9 | 37 | 40.9±20.5 | <0.001 |
| GCC thickness | (<5% level) | 15 | 12.3±8.0 | 49 | 38.6±20.0 | <0.001 |
| Area of RNFL defects (mm2) | ||||||
| 4 sector thickness | (<5% level) | 22 | 1.40±1.08 | 42 | 3.02±1.40 | <0.001 |
| 12 sector thickness | (<5% level) | 14 | 0.83±0.49 | 50 | 2.92±1.37 | <0.001 |
| 36 sector thickness | (<5% level) | 5 | 0.72±0.33 | 59 | 2.61±1.47 | 0.005 |
| Thickness map | b | 2 | 0.90±0.93 | 62 | 2.51±1.50 | 0.10 |
| Significance map | (<5% level) | 1 | 0.24 | 62 | 2.50±1.49 | 0.10 |
| NFL thickness | (<5% level) | 14 | 1.01±0.70 | 50 | 2.87±1.42 | <0.001 |
| GCL+IPL thickness | (<5% level) | 27 | 1.53±1.24 | 37 | 3.14±1.32 | <0.001 |
| GCC thickness | (<5% level) | 15 | 1.04±0.68 | 49 | 2.90±1.42 | <0.001 |
| Average RNFL thickness (depth) (μm) | ||||||
| 4 sector thickness | (<5% level) | 22 | 94.1±10.7 | 42 | 78.7±12.4 | <0.001 |
| 12 sector thickness | (<5% level) | 14 | 95.4±10.7 | 50 | 80.8±13.0 | <0.001 |
| 36 sector thickness | (<5% level) | 5 | 97.8±9.0 | 59 | 82.8±13.6 | 0.02 |
| Thickness map | b | 2 | 102.5±2.1 | 62 | 83.4±13.7 | 0.03 |
| Significance map | (<5% level) | 1 | 104 | 63 | 83.7±13.7 | 0.12 |
| NFL thickness | (<5% level) | 14 | 95.8±10.7 | 50 | 80.7±12.9 | <0.001 |
| GCL+IPL thickness | (<5% level) | 27 | 90.7±12.3 | 37 | 79.1±13.0 | 0.001 |
| GCC thickness | (<5% level) | 15 | 95.7±10.3 | 49 | 80.4±12.8 | <0.001 |
Abbrevaitions: GCC, ganglion cell complex; GCL, ganglion cell layer; IPL, inner plexiform layer; NFL, nerve fiber layer; RNFL, retinal nerve fiber layer; SD, standard deviation.
a
Mann–Whitney U test.
b
The RNFL defect was defined as a wedge-shaped dark blue area surrounding an abrupt color scale change in the RNFL thickness map, at least larger than the diameter of a major retinal vessel.