Table 2. Particle size for representative samples from S1–S5.
| Supplier |
Day 1 |
Day 14 |
Day 1–14 |
||
|---|---|---|---|---|---|
| Particle size (μm) | Pa | Particle size (μm) | Pb | Pc | |
| S1 | 3.5±0.3 | NS | 3.2±0.1 | <0.001 | NS |
| S2 | 3.6±0.3 | 3.3±0.1 | <0.05 | ||
| S3 | 3.4±0.1 | 3.5±0.0 | <0.05 | ||
| S4 | 3.1±0.3 | 2.9±0.1 | NS | ||
| S5 | 3.2±0.6 | 2.9±0.9 | NS | ||
| Reference bevacizumab | 3.4±0.7 | 3.7±0.4 | NS | ||
Values given are means±SD.
S1–S5, samples from suppliers S1–S5. P-values are based on a Student's t-test and analysis of variance.
a
Comparison between representative batches from different suppliers at day 1.
b
Comparison between representative batches from different suppliers at day 14.
c
Comparison between measurements of a representative batch from a single supplier at day 1 and day 14.