Scheme 1.
One-pot Orru-3CR of imidazoline PB2a and optimization by amidation yielding derivative PB11 with improved affinity and water solubility. (TBD = 1,5,7-triazabicyclo[4.4.0]dec-5-ene).
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.