Figure 2.
Map of human and Cynomolgus monkey IL4RA polymorphisms significantly associated with allergen-induced clinical outcomes. IL4RA introns and promoter are depicted in grey; exons and 3’ untranslated region in black. Genomic information primarily adapted from the human and Rhesus UCSC genome Browser. Rhesus sequence (the closest publically available sequence to Cynomolgus) contains gaps, therefore map is not to scale. Cyno IL4RA SNP LD plot and SNP correlation (r2) generated in Haploview v4.1.