Table 2.

Age-Adjusted Spearman Partial Correlation Coefficients of Plasma Adiponectin and Soluble Leptin Receptor with Lifestyle Factors and Biomarkers among Control Participants in the Nurses’ Health Study (1990) and the Health Professionals Follow-up Study (1994)^a

Variable	Adiponectin, μg/mL		Soluble Leptin Receptor, ng/mL
	Women	Men	Women	Men
Soluble Leptin Receptor, ng/mL	0.29b	0.37b	-	-
Body mass index, kg/m2	−0.31b	−0.24b	−0.37b	−0.40b
Waist circumference, inch	−0.32b	−0.21b	−0.33b	−0.38b
Waist-to-hip ratio	−0.32b	−0.26b	−0.34b	−0.26b
Physical activity, MET-hours/week	0.05d	0.06d	0.09d	0.15b
Pack-years of smoking	−0.02d	−0.01d	−0.15c	−0.15b
Alcohol consumption, g/day	0.11c	0.08	−0.03d	<0.001d
DASH score	0.03d	0.09d	0.09d	0.20b
CRP, mg/L	−0.25b	−0.17b	−0.16b	−0.18b
IL-6, pg/mL	−0.22b	−0.11c	−0.23b	−0.21b
sTNFR-2, ng/mL	−0.14b	−0.11c	−0.19b	−0.11c
25(OH)D, ng/mL	0.09c	0.08d	0.03d	0.14b
C-Peptide, ng/mL	−0.38b	−0.30b	−0.44b	−0.30b
IGF-1/IGFBP-3 ratio	0.01d	0.02d	−0.25b	−0.08d

Abbreviations: 25(OH)D, 25-hydroxyvitamin D; CRP, C-reactive protein; DASH, Dietary Approaches to Stop Hypertension; MET, metabolic equivalent = (caloric need/kilogram body weight per hour activity)/(caloric need/kilogram body weight per hour at rest); IGF-1, insulin-like growth factor-1; IGFBP-3, insulin-like growth factor binding protein-3; IL-6, interleukin-6; sTNFR-2, soluble tumor necrosis factor receptor 2;.

^aCorrelation analysis for biomarkers was restricted to the participants with measurement information available, as described in the footnote of Table 1.

^bP<0.001

^cP< 0.05

^dP≥0.05