. Author manuscript; available in PMC: 2013 Sep 13.

Published in final edited form as: J Immunol. 2010 Feb 10;184(6):2847–2854. doi: 10.4049/jimmunol.0903647

Table II.

Adenosine downregulates telomerase activity in CD8 T lymphocytes

	ADA Inhibitor	Adenosine/ADA Inhibitor
Donor
1	0.888	0.520
2	0.936	0.374
3	0.926	0.687
4	1.036	0.519
Mean ± SD	0.946 ± 0.0632	0.493 ± 0.0826
value	0.14	0.00031

Purified CD8⁺ T cells from cultures established from four individual donors were isolated after the second stimulation (with Ab-coated microbeads). The TRAP assay was performed on 2500 cell equivalents. For each donor, the fold change in telomer-ase activity of cultures containing either the ADA inhibitor alone or adenosine plus the ADA inhibitor as compared with the DMSO control is shown.