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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Immunol. 2013 Aug 5;191(5):2372–2383. doi: 10.4049/jimmunol.1300107

Figure 2. DAP-deficient T cells show impaired early TCR signaling following antigen challenge in vivo.

Figure 2

Wild-type and ADAP−/− DO11 T cells (200,000 T cells) were co-transferred into recipient mice challenged with either IFA alone (shaded histograms, -Ag) or IFA/OVA (black histograms, +Ag) in the ear. Draining LNs were harvested at the indicated time points, fixed and stained for phosphorylated c-Jun and S6. Plots are representative of 4 independent experiments.