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. Author manuscript; available in PMC: 2013 Sep 13.
Published in final edited form as: Science. 2010 Oct 29;330(6004):612–616. doi: 10.1126/science.1191078

Figure 1. Cis and trans epigenetic signals.

Figure 1

(A) A trans epigenetic signal (yellow circle) is transmitted by partitioning of the cytosol during cell division and maintained by feedback loops. As an example here we depict a simple regulatory loop in which the epigenetic signal induces its own expression. (B) Cis signals (yellow flag) are molecular signature physically associated with the DNA and inherited via chromosome segregation during cell division.