. Author manuscript; available in PMC: 2013 Sep 13.

Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2012 Oct 9;51(11):1173–1184. doi: 10.1016/j.jaac.2012.08.028

Table 2.

Comparison of the two randomized treatment groups on symptom scores at key time points and comparison of change in scores over time. Lower score is better on all scales.

Measure	Treatment Group	Baseline Mean (sd)	Mean Diff (sd) at Baseline p-value	End of RUPP Main Study (24Weeks) Mean (sd)	Mean Diff (sd) at 24 Weeks p-value	End of Follow-Up Mean (sd)	Mean Diff (sd) At Follow-up p-value	Change BL to 24wk Mean Diff (sd) p-value ES d	Change BL to FU Mean Diff (sd) p-value ES d
HSQ mean	MED	4.41 (1.51)	0.052 (1.58) p = 0.88	1.85 (1.32)	0.57 (1.28) p = 0.0431	2.12 (1.87)	0.28 (1.64) p = 0.43	0.52 (1.63) p = 0.14 d = 0.32	0.23 (1.86) p = 0.57 d = 0.12
HSQ mean	COMB	4.35 (1.63)	0.052 (1.58) p = 0.88	1.28 (1.26)	0.57 (1.28) p = 0.0431	1.84 (1.46)	0.28 (1.64) p = 0.43	0.52 (1.63) p = 0.14 d = 0.32	0.23 (1.86) p = 0.57 d = 0.12
HSQ Yeses	MED	19.67 (3.05)	0.59 (3.96) p = 0.47	12.00 (6.80)	1.59 (6.89) p= 0.29	13.67 (7.04)	0.98 (6.40) p = 0.48	1.00 (6.79) p = 0.50 d = 0.15	0.39 (6.85) P = 0.79 d = 0.06
HSQ Yeses	COMB	19.08 (4.48)	0.59 (3.96) p = 0.47	10.41 (6.96)	1.59 (6.89) p= 0.29	12.69(5.91)	0.98 (6.40) p = 0.48	1.00 (6.79) p = 0.50 d = 0.15	0.39 (6.85) P = 0.79 d = 0.06
ABC I Irritability Subscale	MED	29.86 (6.40)	0.82 (6.32) p= 0.55	15.64 (8.47)	4.58 (7.68) p = 0.0075	15.25 (3.36)	1.15 (9.50) p = 0.58	3.76 (8.19) p = 0.038 d = 0.46	0.33 (9.93) p = 0.88 d = 0.03
ABC I Irritability Subscale	COMB	29.04 (6.26)	0.82 (6.32) p= 0.55	11.06 (7.07)	4.58 (7.68) p = 0.0075	14.10 (3.60)	1.15 (9.50) p = 0.58	3.76 (8.19) p = 0.038 d = 0.46	0.33 (9.93) p = 0.88 d = 0.03
ABC II Lethargy Subscale	MED	18.42 (8.20)	4.00 (8.88) p = 0.0413	6.81 (6.97)	2.57 (5.95) p= 0.0645	7.39 (6.83)	2.74 (5.93) p= 0.0365	−1.43 (7.17) p = 0.36 d = 0.20	−1.26 (8.00) p = 0.47 d = 0.16
ABC II Lethargy Subscale	COMB	14.41 (9.33)	4.00 (8.88) p = 0.0413	4.24 (5.11)	2.57 (5.95) p= 0.0645	4.65 (5.21)	2.74 (5.93) p= 0.0365	−1.43 (7.17) p = 0.36 d = 0.20	−1.26 (8.00) p = 0.47 d = 0.16
ABC III Stereotypy Subscale	.MED	10.50 (5.44)	2.87 (5.25) p = 0.0139	6.58 (5.68)	3.72 (4.55) p = 0.0010	5.61(5.31)	1.55 (4.42) p = 0.14	0.85(3.96) −p = 0.33 d = 0.21	−1.32 (4.95) p = 0.22 d = 0.27
ABC III Stereotypy Subscale	COMB	7.63 (5.14)	2.87 (5.25) p = 0.0139	2.86 (3.56)	3.72 (4.55) p = 0.0010	4.06 (3.67)	1.55 (4.42) p = 0.14	0.85(3.96) −p = 0.33 d = 0.21	−1.32 (4.95) p = 0.22 d = 0.27
ABC IV Hyperactivity Subscale	MED	36.08 (6.36)	1.73 (8.10) p = 0.30	21.83 (10.96)	6.46 (10.39) p = 0.0054	18.94 (11.42)	1.57(11.63) p = 0.54	4.73(9.25) p = 0.02 d = 0.51	−0.16 (10.67) p = 0.95 d = 0.01
ABC IV Hyperactivity Subscale	COMB	34.35 (9.13)	1.73 (8.10) p = 0.30	15.37 (9.98)	6.46 (10.39) p = 0.0054	17.37(11.78)	1.57(11.63) p = 0.54	4.73(9.25) p = 0.02 d = 0.51	−0.16 (10.67) p = 0.95 d = 0.01
ABC V Inappropriate Speech Subscal	MED	5.83(3.90)	0.03(3.69) p = 0.97	2.92 (3.44)	0.49 (3.00) p = 0.46	3.22(3.36)	−0.05 (3.03) p = 0.94	0.46 (3.14) p = 0.51 d = 0.15	−0.08 (3.24) p = 0.91 d = 0.02
ABC V Inappropriate Speech Subscal	COMB	5.80(3.53)	0.03(3.69) p = 0.97	2.43 (2.64)	0.49 (3.00) p = 0.46	3.27 (2.77)	−0.05 (3.03) p = 0.94	0.46 (3.14) p = 0.51 d = 0.15	−0.08 (3.24) p = 0.91 d = 0.02

Note: ABC = Aberrant Behavior Checklist; MED = medication alone; COMB = medication + parent training in behavior management; Tx = treatment; sd = standard deviation; Diff = Difference; FU = follow up; BL = Baseline; wk = week; ES = effect size d.