Table 1.

Depression-like behavior and plasma corticosterone in floxed GR and FBGRKO-T50 mice on the original C57BL/6 × 129 × CBA background (Boyle et al., 2005; Furay et al., 2008; Solomon et al., 2012).

	Forced Swim Immobility (5 sec bins/15 min)	Tail Suspension Immobility (5 sec bins/15 min)	Sucrose Preference (% total fluid intake)	Plasma Corticosterone (μg/dl)
Floxed GR	21±9 (5)	27±5 (10)	76.00±2.43 (8)	50.5±7.7 (5)
FBGRKO-T50	55±12 (5)	39±7 (7)	70.01±4.38 (8)	58.8±6.5 (5)

Immobility was measured, as reported by Boyle et al., as the number of 5 sec bins the mouse was completely immobile during an 8 min tail suspension or a 15 min forced swim test (Boyle et al., 2005). Sucrose preference was measured as a percentage of daily total fluid intake and averaged over 10 days, as reported by Boyle et al. (Boyle et al., 2005). Plasma corticosterone was measured immediately after the 15 min forced swim test. Group sizes are indicated by the number in parentheses.