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OGD does not affect PC GABAA receptor sensitivity to diazepam or zolpidem. (A) Average concentration-response relationships for diazepam from control and OGD PCs. The average EC50 for control PCs was 2.27 ± 0.4 µm (n = 7). For OGD cells the average EC50 was 2.81 ± 0.4 µM (n = 6). (B) Average concentration–response relationships for zolpidem from control and OGD PCs. The average EC50 for control cells was 465.7 ± 75.9 nm (n = 9). The average OGD cell EC50 was 482.6 ± 62.4 nm (n = 8).
