. Author manuscript; available in PMC: 2013 Sep 13.

Published in final edited form as: Int J Radiat Biol. 2011 Jul 5;87(10):1052–1060. doi: 10.3109/09553002.2011.587860

Table II.

Effects of Carbamazepine on Radiosensitivity of 32D cl 3 Wells When Administered Both Before and After Irradiation

Drug Concentration Added	D₀ (Gy)	Ñ
Control	1.2 ± 0.1	1.0 ± 0.1
10 μM Before Irradiation	1.5 ± 0.1 (p = 0.040)	1.1 ± 0.1
10 μM After Irradiation	1.1 ± 0.1	2.3 ± 0.3 (p = 0.032)
10 μM Before and After Irradiation	1.1 ± 0.1	1.9 ± 0.2 (p = 0.033)

4-well plates with 500 or 1000 cells per plate were scored at day 7 for colonies of ≥ 50 cells as described in the Materials and Methods. The p values compare each drug above to non-drug treated irradiated cells using the SHMT model (Epperly et al. 2003).