Table 1.

Anti-inflammatory effect of the aqueous-methanol extract of P. verticillatum Rhizomes (PR) in carrageenan-induced hind paw edema in rats

Group	Dose mg/kg	Increase in paw volume (Mean ± SEM) in mL
		1 h	2 h	3 h	4 h	5 h
Saline	10	0.70 ± 0.031	0.69 ± 0.040	0.69 ± 0.049	0.70 ± 0.067	0.72 ± 0.053
PR	50	0.64 ± 0.045 (08.57%)	0.61 ± 0.054 (11.59%)	0.55 ± 0.049 (20.29%)	0.54 ± 0.053 (22.85%)	0.55 ± 0.049 (23.61%)
	100	0.56 ± 0.036 (20.00%)	0.50 ± 0.049* (27.53%)	0.37 ± 0.058** (46.37%)	0.39 ± 0.062** (44.29%)	0.47 ± 0.062* (34.72%)
	200	0.47 ± 0.040* (32.86%)	0.35 ± 0.067** (49.27%)	0.24 ± 0.045** (65.22%)	0.31 ± 0.053** (55.71%)	0.34 ± 0.062** (52.78%)
Aspirin	100	0.23 ± 0.040** (67.14%)	0.19 ± 0.017** (72.46%)	0.17 ± 0.031** (78.1%)	0.18 ± 0.022** (75.71%)	0.18 ± 0.036** (75.00%)

Experimental data are expressed as mean ± S.E.M. for group of at least six animals. One- way ANOVA was utilized as judgment test of significant differences among groups followed by Dunnett’s multiple comparison post-test. A probability of ^*P < 0.05 or **P < 0.01 was considered significant from control. Protection (%) is shown in parenthesis.