Table 4.

Adjusted Associations Between CAD Use and Nonuse and Invasive Breast Cancer Stage, Size, and Lymph Node Status^*

Outcome	Adjusted OR Associated With CAD Use vs Nonuse (95% CI)	P Value
Stage (n = 30 681)
Stage I (vs. II, III, or IV)	1.15 (1.09–1.22)	<0.001
Stages I or II (vs. III or IV)	1.27 (1.14–1.41)	<0.001
Size (n = 31 071)
Size <1 cm (vs. ≥1 cm)	1.10 (1.04–1.16)	<0.001
Size <2 cm (vs. ≥2 cm)	1.18 (1.10–1.25)	<0.001
Lymph node status (n = 28 237)
Negative (vs. positive)	1.15 (1.08–1.24)	<0.001

CAD = computer-aided detection; OR = odds ratio.

^*Adjusted for age, race or ethnicity, rural vs. urban residence, median income of elderly residents within the same ZIP code, time since previous mammogram, use of CAD on the previous examination, presence of stable and unstable comorbid conditions, digital vs. film mammography, year of examination, and SEER (Surveillance, Epidemiology and End Results) region. Sample sizes differ from the total number of invasive cancer cases (n = 36 270) because of missing or unknown stage, size, or node status or missing covariates.