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Model comparison. Curve (a) Trapped tracer activity (in arbitrary unit) versus time (in minutes) from Equation 3, assuming irreversible trapping, and the input function of Vriens et al. for 18F-FDG was used [15]. Curve (b) (full line) Z-F function, i.e. ATot(t = 60) * exp(−λt) (the value for ATot(t=60) was taken from curve a). Curve (c) (dotted line) Z-F function with ATot(t = 84) (instead of ATot(t = 60)) that gives similar AUC for the two models.
