Table 1. Baseline characteristicsa of subjects according to body mass index.
| Normal-weight | Overweight/Obese | |||
|---|---|---|---|---|
| n = 1035 | n = 648 | P Value | ||
| HOMA – IR (uU/ml .mmol/ml) | 1.42 (1.00 - 1.99) | 2.41 (1.70 - 3.52) | <0.001 | |
| Insulin Resistance (%) | 115 (11.11) | 274 (42.28) | <0.001 | |
| Demographics | ||||
| Age (Years) | 50.83 ± 15.54 | 53.83 ± 12.58 | <0.001 | |
| Male (%) | 375 (36.23) | 272 (26.28) | <0.001 | |
| Clinical Characteristics | ||||
| Body Mass Index (kg/m2) | 21.08 ± 1.98 | 26.57 ± 2.30 | <0.001 | |
| Waist circumference(cm) | 77.50 ± 7.62 | 90.52 ± 7.78 | <0.001 | |
| History of Hypertension (%) | 123 (11.88) | 179 (27.62) | <0.001 | |
| History of coronary heart disease (%) | 17 (1.64) | 15 (2.31) | 0.36 | |
| History of stroke (%) | 2 (0.19) | 3 (0.44) | 0.38 | |
| Current smoker (%) | 122 (11.79) | 87 (13.43) | 0.31 | |
| Current alcohol use (%) | 53 (5.12) | 41 (6.32) | 0.29 | |
| Education attainment High school or above(%) | 467 (45.12) | 245 (37.81) | <0.001 | |
| Physical inactivity (%) | 585 (56.52) | 370 (57.10) | 0.82 | |
| Systolic blood pressure (mm Hg) | 124.01 ± 19.55 | 133.51 ± 19.25 | <0.001 | |
| Diastolic blood pressure (mmHg) | 75.47 ± 10.76 | 81.51 ± 10.34 | <0.001 | |
| Laboratory | ||||
| Serum creatitine (umol/L) | 71.40 ± 16.01 | 75.30 ± 16.39 | <0.001 | |
| eGFR ( ml/min/1.73m2) | 102.57 ± 22.59 | 96.41 ± 20.59 | <0.001 | |
| Serum uric acid (umol/L) | 331.01 ± 88.45 | 378.48 ± 98.18 | <0.001 | |
| ACR (mg/g)) | 7.96 (5.48 - 12.38) | 8.97（5.92 - 15.82） | <0.001 | |
| Fasting glucose (mmo/l) | 4.68 ± 0.47 | 4.92 ± 0.61 | <0.001 | |
| Serum C-reactive protein (mg/l) | 0.67 (0.33 - 1.53) | 1.63（0.82 - 3.34） | <0.001 | |
| Serum triglyceride (mmol/L) | 1.05 (0.77 - 1.46) | 1.55 (1.08 - 2.19) | <0.001 | |
| Serum low density lipoprotein (mmol/l) | 3.08 ± 0.89 | 3.31 ± 0.90 | <0.001 | |
| Serum high density lipoprotein (mmol/l) | 1.60 ± 0.33 | 1.45 ± 0.28 | <0.001 | |
a Mean ± SD or median (25th to 75th percentiles) for continuous variables and absolute and relative (%) values for category variables are presented.
HOMA-IR: Homeostatic model assessment of insulin resistance; eGFR: estimated Glomerular filtration rate
ACR: Urinary albumin to creatinine ratio