Table 2. Interaction surfaces between the α and β-subunits of MPP and between the β-subunit and the bound peptide substrate in MPP active site.
α-MPP versus β-MPP
|
Substrate versus β-MPP
|
|||
---|---|---|---|---|
Start value | End value | Start value | End value | |
WT | 2110 Å2 | 1812 Å2 | - | - |
WT + substrate | 2110 Å2 | 2336 Å2 | 886 Å2 | 886 Å2 |
ΔGRL MPP | 1850 Å2 | 1907 Å2 | - | - |
ΔGRL MPP + substrate | 1850 Å2 | 1428 Å2 | 886 Å2 | 861 Å2 |