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. 2013 Sep 13;8(9):e75620. doi: 10.1371/journal.pone.0075620

Figure 3. Summary of MHC Class I and CD4 downregulation.

Figure 3

The mean and standard deviation of HLA-A*02 (A) and CD4 (B) downregulation by control and subject-derived nef alleles from at least three separate infections is shown. Difference from % downregulation by NL4-3 Nef was evaluated with a two-tailed t test, and differences with a p-value <0.05 are marked with an *. Differences between gut and plasma quasispecies from the same subject were also evaluated with a two-tailed t test, and pairs with significant differences are marked with a horizontal bar with the p-value indicated above the bar.