Table 3. CYP3A4, PXR, CAR and PPARα mRNA expression in cirrhotic and normal liver samples.

	Intra-group variability in mRNA expression		Relative mRNA expression
	Normal (n=12)	Cirrhosis (n=28)	Normal (n=12)	Cirrhosis (n=28)	P-value
CYP3A4 mRNA	449-fold	209-fold	5.91 ± 1.29	21.76 ± 2.65	2.04E-07
PXR mRNA	490-fold	14-fold	4.45 ± 0.87	6.15 ± 0.45	0.04
CAR mRNA	172-fold	24-fold	3.55 ± 0.71	6.26 ± 0.43	0.0008
PPARα mRNA	3637-fold	225-fold	0.06 ± 0.01	0.63 ± 0.06	1.90029E-12