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Quantitation of Cu
| Method | Object | Cu concentration |
|---|---|---|
| AAS (45) |
Plasma | 15-20μM |
| CSF | 0.5μM | |
| μXRF | Localized Cu accumulation in cell |
~100-500 mM* |
| Area in cell without Cu accumulation |
~130-300 μM |
This number is obtained with the assumption that localized Cu accumulation is about 1 μm in diameter and the signal detected in μXRF pixel on 10 μm thick section comes from single accumulation.
