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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Aging Cell. 2013 Jun 11;12(5):763–771. doi: 10.1111/acel.12102

Figure 3.

Figure 3

(A) In vivo P/O ratio was depressed with age and fully restored one hour after SS-31 injection. (B) Resting ATPase rate was significantly lower in old mice and recovered one hour following SS-31 treatment, while (C) O2 consumption was unchanged. (D) After ischemia, PCr recovered to resting concentration at a faster rate in old mice following SS-31 treatment, revealing (E) a significant increase in ATPmax. SS-31 had no observed affect on these measures of in vivo mitochondrial function in young mice. Means ± SEM. n = 5–7 per group. **p<0.01 relative to age-matched control. ##p<0.01 relative to young control.