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(A) Plots of force vs. time during repetitive tetanic stimuli were distinctly different in old control and old SS-31-treated mice, with SS-31 treatment slowing the rate and magnitude of force decay. (B) Net force maintained by TA muscle at the end of fatigue experiments was significantly higher in SS-31-treated mice. (C) Maximum specific force and (D) the force-frequency response in old muscle was the same regardless of SS-31 treatment. Means ± SEM. n = 6–7 per group. *p<0.05.
