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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Lab Anim. 2013 Jun 10;47(4):257–265. doi: 10.1177/0023677213489548

Figure 4.

Figure 4

β cell mass is decreased to a similar extent in streptozotocin (STZ)-Fed and STZ-Fasted C57BL/6J mice. Pancreata from treated C57BL/6J mice were harvested 25 days after multiple low dose (MLD)-STZ injections and sectioned. Sections were stained for insulin and counterstained with hemotoxylin. (a–c) Representative pancreatic sections at 10× magnification are shown from each treatment group. (d) Average β cell mass in treated mice. Results are expressed as the means ± SEM. n = 4 mice per group. *P < 0.05 compared with Control mice that were ad libitum fed (phosphate buffered saline (PBS)-Fed) at the time of injection.