Table 3. [3H]-Quinpirole D2R agonist saturation binding kinetics.
Group | Kd (nM ± SEM) | Bmax (fmol/mg protein ± SEM) |
---|---|---|
WT/Sac | 3.322 ± 0.458 | 117.7 ± 15.5 |
WT/PNE | 3.348 ± 0.599 | 128.0 ± 15.2 |
HET/Sac | 4.562 ± 0.565 | 127.8 ± 15.7 |
HET/PNE | 7.128 ± 0.606*,** | 119.5 ± 9.3 |