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. 2013 Sep 10;5(3):190–193.

Table 3.

Comparisons of cardiorespiratory and metabolic responses at the end of running in the heat between acetaminophen and placebo pre-treatment

Variable Paracetamol (N=7) Placebo (N=7) P-value


Mean SD Mean SD
Running Time (min) 47.5 (15.5) 45.2 (13.1) 0.42
Delta Body Mass (kg) 1.17 (0.62) 1.13 (0.58) 0.50
Hematocrit (%) 44.2 (2.4) 44.5 (4.1) 0.90
HR (bpm) 185.0 (11.6) 185.3 (9.9) 0.88
VO2 (mL/min/kg) 56.0 (10.2) 57.4 (6.8) 0.55
RER 0.82 (0.16) 0.84 (0.03) 0.76
BPsyst (mmHg) 121.3 (18.9) 133.0 (22.6) 0.15
BPdiast (mmHg) 70.0 (11.5) 76.6 (13.6) 0.22
Blood Lactate (mmol/L) 6.2 (1.9) 6.2 (2.4) 0.96
RPE 18.4 (0.79) 18.1 (0.69) 0.36

HR: heart rate, VO2: oxygen uptake, RER: respiratory exchange ratio, BPsyst: systolic blood pressure, Bpdiast: diastolic blood pressure, RPE: ratings of perceived exertion.