Table 4.
Case | Hip/knee | Indication | Number of cultures sent | Number of positive cultures | Organism | Treatment | Subsequent infection cultures | Followup (months) |
---|---|---|---|---|---|---|---|---|
1 | Knee | PJI Stage 2 | 4 | 1 | Candida albicans/Enterobacter cloacae | No | NA | 6 |
2 | Knee | Loosening | 4 | 1 | Alternaria/coagulase-negative Staphylococcus | No | NA | 62 |
3 | Hip | PJI Stage 2 | 4 | 1 | Penicillium | Voriconazole | NA | 32 |
4 | Knee | PJI Stage 2 | 3 | 1 | Aspergillus | No | NA | 79 |
5 | Hip | Loosening | 3 | 1 | Cladosporium | No | NA | 25 |
6 | Hip | Loosening | 3 | 1 | Penicillium | No | NA | 39 |
7 | Knee | Loosening | 3 | 1 | Aureobasidium | No | NA | 75 |
8 | Knee | PJI Stage 2 | 3 | 1 | Candida albicans | No | NA | 1 |
9 | Hip | PJI Stage 2 | 3 | 1 | Aspergillus fumigatus | No | NA | 3 |
10 | Hip | PJI Stage 2 | 3 | 1 | Dematiaceous | No | NA | 27 |
11 | Hip | Loosening | 3 | 1 | Penicillium | No | NA | 42 |
12 | Hip | PJI Stage 2 | 2 | 1 | Paecilomyces | No | NA | 82 |
13 | Hip | PPFx | 2 | 1 | Penicillium | No | NA | 2 |
14 | Hip | Instability | 2 | 1 | Rhodotorula minuta | Caspofungin | NA | 79 |
15 | Hip | PJI Stage 2 | 2 | 1 | Candida albicans | No | NA | 67 |
16 | Hip | Loosening | 1 | 1 | Rhodotorula | No | NA | 38 |
17 | Knee | PJI Stage 2 | 1 | 1 | Penicillium | No | NA | 15 |
18 | Hip | PJI Stage 2 | 2 | 1 | Candida albicans/VRE | Fluconazole | VRE | 39 |
19 | Knee | Loosening | 1 | 1 | Candida parapsilosis | No | Candida parapsilosis, MSSA | 47 |
* Only patients with a minimum followup of 12 months were included in the analysis of true-/false-positive rates; PJI = periprosthetic joint infection; PPFx = periprosthetic fracture; VRE = vancomycin-resistant Enterococcus; MSSA = methicillin-sensitive Staphylococcus aureus; NA = not applicable.