TABLE 1. Data from metabolic cages studies.
Group name | UNOxV (μmol/day) | IISOV (ng/day) | UTBARSV (μmol/day) | UH2O2V (μmol/day) |
---|---|---|---|---|
I3C-induced + untreated | 19.68 ± 1.44# | 21.74 ± 2.45 | 0.24 ± 0.06 | 0.46 ± 0.09 |
I3C-induced + c-AUCB | 9.88 ± 0.91* | 19.86 ± 1.74 | 0.32 ± 0.07 | 0.37 ± 0.07 |
I3C-induced + L-NAME | 4.09 ± 0.99 | 21.72 ± 1.24 | 0.27 ± 0.05 | 0.41 ± 0.05 |
I3C-induced + L-NAME + c-AUCB | 4.14 ± 0.56 | 22.14 ± 1.96 | 0.25 ± 0.04 | 0.43 ± 0.05 |
I3C-induced + L-NAME + RAS blockade | 3.89 ± 1.01 | 20.72 ± 2.71 | 0.31 ± 0.06 | 0.39 ± 0.07 |
Noninduced + untreated | 11.98 ± 0.91* | 25.14 ± 2.02 | 0.27 ± 0.04 | 0.43 ± 0.06 |
Noninduced + c-AUCB | 10.42 ± 0.96* | 20.81 ± 1.96 | 0.32 ± 0.06 | 0.47 ± 0.09 |
Noninduced + L-NAME | 4.12 ± 0.56 | 22.42 ± 1.76 | 0.29 ± 0.05 | 0.38 ± 0.06 |
Noninduced + L-NAME + c-AUCB | 4.86 ± 0.64 | 19.86 ± 2.64 | 0.31 ± 0.06 | 0.42 ± 0.06 |
Noninduced + L-NAME + RAS blockade | 5.04 ± 0.86 | 25.17 ± 2.89 | 0.28 ± 0.07 | 0.43 ± 0.07 |
c-AUCB, treatment with the soluble epoxide hydrolase inhibitor; I3C, administration of indole-3-carbinol; IISOV, urinary 8-isoprostane excretion; L-NAME, treatment with nitric oxide synthase inhibitor; RAS, renin–angiotensin system; UH2O2V, urinary hydrogen peroxide excretion; UNOxV, urinary nitrate/nitrite excretion; UTBARSV, urinary thiobarbituric acid-reactive substances excretion.
P < 0.05 vs. unmarked values.
P < 0.05 vs. all values.