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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Hypertens. 2013 Feb;31(2):321–332. doi: 10.1097/HJH.0b013e32835b50aa

TABLE 2. Basal values of mean arterial pressure, renal function and electrolyte excretion.

Group name MAP (mmHg) GFR (ml/min per g) RBF (ml/min per g) UNaV (μmol/min per g) FENa (%) V (μl/min per g)
I3C-induced + untreated 162 ± 3@ 1.45 ± 0.27* 6.03 ± 0.34# 1.48 ± 0.25@ 1.32 ± 0.22@ 13.51 ± 1.48@
I3C-induced + c-AUCB 134 ± 3* 1.99 ± 0.19* 9.24 ± 0.62@ 1.91 ± 0.27@ 2.04 ± 0.29@ 12.18 ± 1.81@
I3C-induced + L-NAME 163 ± 4@ 0.69 ± 0.11 2.61 ± 0.17 0.29 ± 0.09* 0.25 ± 0.07* 3.82 ± 0.34*
I3C-induced + L-NAME + c-AUCB 161 ± 3@ 0.61 ± 0.14 2.09 ± 0.24 0.35 ± 0.06* 0.33 ± 0.04* 4.11 ± 0.29*
I3C-induced + L-NAME + RAS blockade 109 ± 4 0.74 ± 0.14 3.69 ± 0.23* 0.66 ± 0.05# 0.71 ± 0.06# 6.52 ± 0.27
Noninduced + untreated 111 ± 3 1.89 ± 0.17* 8.02 ± 0.41# 0.43 ± 0.06* 0.39 ± 0.08* 4.98 ± 0.36*
Noninduced + c-AUCB 112 ± 3 2.21 ± 0.21* 7.22 ± 0.53# 0.47 ± 0.05* 0.44 ± 0.09* 4.66 ± 0.42*
Noninduced + L-NAME 136 ± 4* 0.71 ± 0.19 2.37 ± 0.16 0.09 ± 0.02 0.11 ± 0.03 2.54 ± 0.22
Noninduced + L-NAME + c-AUCB 135 ± 5* 0.65 ± 0.11 1.99 ± 0.21 0.14 ± 0.04 0.16 ± 0.05 2.63 ± 0.21
Noninduced + L-NAME + RAS blockade 110 ± 4 0.73 ± 0.14 3.71 ± 0.28* 0.29 ± 0.04* 0.33 ± 0.06* 3.61 ± 0.18*

c-AUCB, treatment with the soluble epoxide hydrolase inhibitor; FENa, fractional sodium excretion; GFR, glomerular filtration rate; I3C, administration of indole-3-carbinol; L-NAME, treatment with nitric oxide synthase inhibitor; MAP, mean arterial pressure; RAS, renin-angiotensin system; RBF, renal blood flow; UNaV, absolute sodium excretion; V, urine flow.

*

P < 0.05 vs. unmarked values.

#

P < 0.05 vs. marked values.

@

P < 0.05 vs. all values.