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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Stat Med. 2013 May 6;32(22):3944–3954. doi: 10.1002/sim.5834

Table 3.

Estimates for Eli Lilly data

Variable Unconstrained Estimate SE Constrained Estimate SE
Age 1.00 - 1.00 -
ADL1 - - −0.13 0.04
Platelet Count −0.12 0.03 −0.19 0.08
Creat. Clear. −0.70 0.17 −0.81 0.21
Interleukin 6 0.60 0.11 0.70 0.13
# Organ Fail. 0.14 0.06 0.23 0.11
APACHE II2 0.24 0.09 0.33 0.14
1

Baseline index of independence in activities of daily living.

2

Pre-infusion acute physiology and chronic health evaluation II score.