Table 1.
Characteristics of Amish PAPI Study Participants.
| Characteristic, Units | Males (n = 302) | Females (n = 319) | Total (n = 621) |
|---|---|---|---|
| Mean age ± SD | 43.4 ± 12.3 | 46.9 ± 13.8 | 45.2 ± 13.2 |
| Mean body mass index* ± SD | 25.9 ± 3.5 | 28.4 ± 5.4 | 27.2 ± 4.7 |
| Systolic blood pressure ± SD (mm Hg) | 116.7 ± 11.4 | 117.8 ± 14.1 | 117.3 ± 12.8 |
| Diastolic blood pressure ± SD (mm Hg) | 70.9 ± 7.3 | 69.9 ± 7.4 | 70.4 ± 7.3 |
| Hypertension, No. (%) | 17 (5.6) | 24 (7.5) | 41 (6.6) |
| Total cholesterol ± SD (mg/dl) | 206.2 ± 42.7 | 214.4 ± 51.1 | 210.4 ± 47.3 |
| LDL-C ± SD (mg/dl) | 137.4 ± 39.7 | 137.3 ± 47.4 | 137.4 ± 43.8 |
| HDL-C ± SD (mg/dl) | 55.1 ± 14.5 | 61.9 ± 15.1 | 58.6 ± 15.2 |
| Triglycerides ± SD (mg/dl) | 68.7 ± 39.3 | 75.7 ± 42.3 | 72.3 ± 40.9 |
| Hypercholesterolemia, No. (%) | 54 (17.9) | 64 (20.1) | 118 (19.0) |
| Taking aspirin, No. (%) | 6 (2.0) | 2 (0.6) | 8 (1.3) |
| Self-reported diabetes, No. (%) | 1 (0.3) | 2 (0.6) | 3 (0.5) |
| Mean hematocrit ± SD, % | 41.6 ± 2.4 | 37.7 ± 2.3 | 39.6 ± 3.0 |
| Median (IQR) white blood cell count, X 1000/μL | 5.9 (4.3 -7.5) | 5.9 (4.3 -7.5) | 5.9 (4.3 -7.5) |
| Mean platelet count ± SD, X 100,000/μL | 234.9 ± 45.3 | 246.9 ± 51.7 | 240.6 ± 48.9 |
| Current smoker, No. (%) | 62 (20.5) | 0 (0.0) | 62 (10.0) |
Abbreviations: HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; PAPI, Pharmacogenomics of Anti-platelet Intervention; SD, standard deviation.
SI conversion factors: To convert HDL-cholesterol, LDL-cholesterol, and total cholesterol values to mmol/L, multiply by 0.0259; triglycerides to mmol/L, multiply by 0.0113.
*
Calculated as weight in kilograms divided by height in meters squared