Skip to main content
. Author manuscript; available in PMC: 2014 Jun 15.
Published in final edited form as: Adv Drug Deliv Rev. 2013 Feb 13;65(6):800–810. doi: 10.1016/j.addr.2013.01.003

Fig. 3.

Fig. 3

(A) Drawing of the GI tract of the common brushtail possum and gamma scintigraphy scans of GI tract after oral dosing with small (75–125 μm) radio-labeled with 99mTc exchange resin from 3 to 32 h [79]. (B) Gamma scintigraphy scans of chitosan nanoparticles in the human GI tract; at 3 min the particles remain intact, after 12 min the particle has disintegrated and the particles are moving into the small intestine, after 1 h the granules have attached to the intestinal mucosa in the lower jejunum, and after 1 h 45 min most of the granules have become detached [90]. (C) Localization of an enteric-coated magnetic tablet as determined by gamma scintigraphy from [99mTc]-DTPA labeling. Pictured is the x- and y-plane of the small intestine (SI) and stomach at the 111 min of acquisition [83].