Table 3.
Association of serum myeloperoxidase (MPO) with peripheral arterial disease (PAD): logistic regression models
African-Americans |
Non-Hispanic white individuals |
|||||
---|---|---|---|---|---|---|
Odds ratio | 95% CI | p | Odds ratio | 95% CI | p | |
Model 1 | 1.15 | 0.99–1.34 | 0.066 | 1.64 | 1.19–2.25 | 0.002 |
Model 2 | 1.26 | 1.07–1.48 | 0.005 | 1.48 | 1.08–2.05 | 0.016 |
Model 3 | 1.24 | 1.05–1.47 | 0.010 | 1.54 | 1.08–2.19 | 0.018 |
Model 4 | 1.12 | 0.94–1.34 | 0.193 | 1.52 | 1.06–2.18 | 0.022 |
Odds ratios are shown for 1 standard deviation increase in log MPO.
PAD was defined as ABI < 0.9 or >1.4.
Model 1: Unadjusted.
Model 2: Adjusted for age and sex.
Model 3: Adjusted for age, sex, smoking, diabetes, hypertension, estrogen use, waist circumference, total and HDL cholesterol, and statin use.
Model 4: Adjusted for Model 3 variables and C-reactive protein.