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. Author manuscript; available in PMC: 2014 Apr 15.
Published in final edited form as: Biol Psychiatry. 2013 Feb 16;73(8):774–781. doi: 10.1016/j.biopsych.2012.12.027

Figure 4.

Figure 4

Intra-cranial infusions of L822429 into the central nucleus of the amygdala (CeA) attenuates alcohol self-administration in alcohol-preferring (P) rat. To examine the potential contribution of CeA for the high rates of alcohol self-administration found in P-rats, local infusions of L822429 (7.5 μg/side) were given into this structure, as well as the prefrontal cortex (PFC). Injection sites are shown in panels (A, B). L822429 robustly suppressed alcohol self-administration in P-rats following administration into the CeA (C) but had no effect after PFC infusion (D). ***p < .001. For details, see Methods and Materials and Results. Veh, vehicle. A and B reprinted from Paxinos G, Watson C (2005): The Rat Brain in Stereotaxic Coordinates. 5th ed. Amsterdam: Elsevier Academic Press, with permission.