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. Author manuscript; available in PMC: 2014 Apr 15.
Published in final edited form as: Biol Psychiatry. 2013 Feb 16;73(8):774–781. doi: 10.1016/j.biopsych.2012.12.027

Table 1. Locomotor Activity of P-Rats and Wistar Rats Following Systemic L822429.

L822429
Line Vehicle 15 mg/kg 30 mg/kg
Wistar 2388 ± 307.3 2413 ± 389.1 2155 ± 195.0
P-Rat 2371 ± 122.2 1907 ± 159.7 745 ± 61.2a

L822429 was administered 60 minutes before locomotor activity sessions, and total session activity was measured. L822429 did not affect locomotor activity of Wistar rats at any of the doses given and did not affect the activity of P-rats at 15 mg/kg. At 30 mg/kg, a significant suppression of locomotor activity was observed in P-rats. For detailed statistics, see Methods and Materials and Results.

P-Rat, alcohol-preferring rat.

a

p < .01.